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Navel Orange Worm(NOW) and Pine Processionary Moth(PPM)

Navel orangeworm(NOW) or Amyeloistransitella which belongs to LepidoteraPyrralidea family of insects is an exotic pest that feeds on a variety of fruit and nuts, including citrus.

(Image of Adult Larve& Moth)

The insect is a serious pest forsome nut crops like Almonds and Pistachios as well as Walnuts, Figs &Pomegranates.It also grazes on citrus fruits, causing surface scarring that allows decay-causing organisms to enter the fruit. This reduces fruit quality and causes fruit drop, damaging farmers commercially. Damage level can be 30% to 70% of total crop. It also induces fungal infection in nuts causing carcinogenic Aflatoxin formation. It makes nut unfit for human consumption.

To get good quality nuts and fruits in good yield we need to control growth of this Navel Orange Worm moth(NOW). It can be controlled in modern ways of sustainable farming with the use of non-toxic Insect pheromones instead of pesticides which cause immense damage to environment.For control of Navel Orange Worm(NOW), main pheromone(NOWlure) ingredient used for mating disruption of insect is

11z,13z-Hexadecadien-1-al

Alongwith this ingredientsometimes,11z,13z-Hexadecadien-1-ol

 

and 11z,13z-Hexadecadien-1-ylAcetate

are also used in small quantities.

To make this 11-Dodecyn-1-ol is key intermediate

(CAS No.18202-10-3)

This same intermediate can be used to make pheromone for Pine Processionary Moth (PPM) Thoumetopoeapityocampa. This moth is most destructive for pine and Cedar trees. It causes sever defoliation which can kill tree. Main ingredient of Pitiyolureis z,13-Hexadecen-11-yn-1-yl Acetate

Reaction Scheme:

Please contact ChemHub for more information and how we can make these pheromones for you.

Email: info@chemhub.com

Website: www.chemhub.com

Phone: 908-548-0790

Alkenyl Pheromone Compounds

Aliphatic chemicals with cis/trans double bond at position 10 are used as insect pheromones in many crops. They are synthesized from basic intermediate 10-Undecyn-1-ol. Not only we have expertise to manufacture 10-Undecyn-1-ol but also we have technology to make highly selective cis and trans isomers. We will discuss few of the pheromones in this following blog.

(E)-10-Dodecenyl acetate

(CAS No: 35153-09-4)

 

This pheromone is used for control of Spotted Tentiform Leaf-miner (Phyllonorycter Blancardella) found on Apple Trees. The insect is found in Europe and North America. Small quantity of E-10-Dodecenol is also required in Pheromone formulation.

(Insect and Damage done to Plant)

(Z)-10-Tetradecenyl acetate

(CAS No: 35153-16-3)

This pheromone is used for control of British Leaf-miner (Phyllonorycter Sylvella) and other Leaf-miner (Phyllonorycter Platini) found on Field Maple an ornamental flowering plant.

(Insect and Damage done to Plant)

(10E)-Hexadec-10-en-1-al

CAS No: 72698-30-7

This pheromone is used for control of Yellow Peach Moth or Durian Fruit Borer (Conogothese punctiferalis) which infect Fruit trees like Peach Tree.

(Insect and Damage done to Plant)

(10Z)-Hexadec-10-enyl Acetate

CAS No: 56218-71-4

This pheromone ingredient is used in management of pest infecting wood producing trees like Oak Tree. The insects involved is Oak Leaf Roller (Pseudexenteria spoliana)

(Insect and Damage done to Plant)

(10Z)-Hexadec-10-enyl Acetate

CAS No: 56218-71-4

 

This pheromone ingredient is used in management of pest infecting wood producing trees like Oak Tree. The insects involved is Oak Leaf Roller (Pseudexenteria spoliana)

Please contact us at ChemHub for further information and availability:

ChemHub, Inc.

3 Crossman Road South

Sayreville, NJ 08872

Phone: 908-548-0790

Email: info@chemhub.com

STRATEGIC ALLIANCE: OUR PARTNERS MATTER

Interdependence is not unusual in chemical industry, rather a strategic alliance between two companies or partners is beneficial to undertake mutually dependent projects despite remaining in an independent space. Once two or more partners pool their respective resources, a separate business entity develops which helps in expanding the business into new markets, improve existing product line, develop new technologies and even an edge over the market competitors. Partnership indeed matters as it helps two parties to move towards a common goal that will be beneficiary.

 

Strategic alliance can be both informal and formal. Responsibilities of each member are clearly defined to make the coalition more effective. ChemHub has also entered into strategic alliance to undertake a specific, mutually beneficial project and make deliverables more comprehensive as well as effective. Our growth is thus phenomenal, taking us to new heights.

 

ChemHub maintains key strategic relationships with a number of research and manufacturing partners. The Company has strong experience in the Pheromone and Flavor & Fragrance industry.

Our Key partners include:

  • Chemo Dynamics, New Jersey, US based CRO with over five decades of research knowledge and reputation for producing high quality products with efficient and fast turnaround time.
  • Joint ventures with facilities in India and China that produce large scale manufacturing plants.

With our CRO/CMO partners we deliver a number of services including Custom Synthesis, Process Development, Analytical/ QA Support, Consulting Services, Lead time optimization, Yield-Optimization, Purity, Reaction Time, Hypothermic Reaction, Green Chemistry, Process optimization and Product/Literature Search.

 

As a chemical supplier our partnership aims at Logistic Management including Import/Export and warehouse facilities, Custom Broking, Bulk Chemicals, Waste management and Transportation. We are deft at supplying aroma chemicals, pharmaceutical and specialty chemical intermediates. Our production is focused on Flavor & Fragrance and Pharmaceutical industries as well. With our CRO/CMO partners IN US, India and China, we are focused on small scale research and large scale production.

For more information contact us at info@chemhub.com
Call us at 908-548-0790

ChemHub pheromone products and capabilities

WE ARE THE PHEROMONE EXPERT
Our Exclusive Feedback matters! A whole new world of chemicals awaits you!

Not just pheromone products in ChemHub comprehensive list, we are open to exploring new chemicals relevant to various Pheromone Companies. We can work on new projects for our clients and help them use innovative chemistry to make new products.

 

We not only explore, but also customize new chemicals and pheromones with exclusive feedback from our end. Do not miss a grand collaboration with ChemHub to understand your capabilities and explore new opportunities.

Completion Time

  • We work with speed and precision.
  • We require just a couple of months to complete production schedule of general items.

Our Comprehensive List

Terminal Alkynes

  • 1-Hexyne
  • 1-Heptyne
  • 1-Octyne
  • 1-Nonyne
  • 1-Decyne
  • 1-Dodecyne
  • 1-Tetradecyne

General Process:

  • Acetylene + Alkyl halide
  • Alkene to Dibromo compound followed by Dehydrobromination
  • Aldehyde to Dichloro compound and Dehydrochlorination

α-ώ- Alkynols

9-Decyn-1-Ol (We are even looking into making the raw material inhouse)
10-Undecyn-1-Ol (We have developed the raw material in-house)

General Process:

Alkenol to Dibromocompound followed by Dehydrobromination
Acetylene + Bromo alkanol

Coupling Products

  • 11-Hexadecyn-1-Ol
  • 10-Pentadecyn-1-Ol
  • 5-Decyn-1-Ol
  • 8-Dodecyn-1-Ol
  • 5-Tetradecyn1-Ol
  • 7-Tetradecyn-1-Ol
  • 9-Tetradecyn-1-Ol
  • 11-Tetradecyn-1-Ol
  • 7-Hexadecyn-1-Ol
  • 9-Hexadecyn-1-Ol

General Process:

Alkyne coupling with protected Bromo alkanol
Protected Alkynol coupling with alkyl bromide

2-Alkynols

  • 2-Hexyn-1-Ol
  • 2-Heptyn-1-Ol
  • 2-Octyn-1-Ol
  • 2-Nonyn-1-Ol
  • 2-Decyn-1-Ol
  • 1-Bromo-2-butyne
  • 1-Chloro-2-butyne
  • 2-Butyn-1-Ol
  • 2-Pentyn-1-Ol
  • 1-Bromo-2-pentyne
  • 1-Choro-2-pentyne

General Manufacturing Process

Alkyne coupling with protected Bromo alkanol
Protected Alkynol coupling with alkyl bromide

  • 2-Alkynols
  • 2-Hexyn-1-Ol
  • 2-Heptyn-1-Ol
  • 2-Octyn-1-Ol
  • 2-Nonyn-1-Ol
  • 2-Decyn-1-Ol
  • 1-Bromo-2-butyne
  • 1-Chloro-2-butyne
  • 2-Butyn-1-Ol
  • 2-Pentyn-1-Ol
  • 1-Bromo-2-pentyne
  • 1-Choro-2-pentyne

General Manufacturing Process

Propargyl alcohol coupling with alkyl bromide to get corresponding alcohol followed by halogenation or hydrolysis if required

Alkynoic esters

Methyl Heptine Carbonate
Methyl Hexine Carbonate
Methyl Octine carbonate

General Manufacturing Process

Alkyne coupling with Carbon Dioxide and esterification.
Working on a better scalable process presently.

Other Products (F&F related)

  • Methyl Jasmonate
  • Cis-Jasmone
  • Cis-6-Nonenol
  • Cis-6-Nonenal
  • Delta-Nonalactone
  • Maple Furanone
  • Caramel Furanone
  • Tiglic Acid
  • Angelic Acid
  • Tiglic Aldehyde
  • Butyl Tiglate
  • Phenyl Tiglate
  • Fraision Methyl Ether (CAS No: 4077-47-8)
  • Ethyl Fraison, 2-Ethyl-4-Hydroxy-5-Methyl-3(2H)-Furanone, CAS No: 27538-09-6)?

General Manufacturing Process

Milk lactone is a mixture of 5&6-Decenoic acid. CAS no: 72881-27-7
Damascenone can be made from Safranal and allyl magnesium bromide. CAS no: 23696-85-7

Other Products (Some are under development)

  • 10,12-Pentadecadien-1-Ol
  • 9,11- Tetradecadien-1-Ol
  • 9,11,13-Dodecatrien-1-Ol
  • 1,3,5-Undecatriene
  • Methyl Jasmoate
  • E-5-Decen-1-Ol
  • E-11-Hexadecen-1-Ol
  • Cis-Jasmone
  • 3,6-Nonadiyn-1-ol
  • 4,7-Nonadiyn-1-Ol
  • 9,12-Tetradecadien-1-Ol
  • E-5-Decen-1-Ol
  • E-11-Hexadecen-1-Ol
  • Z-11-Hexadecen-1-Ol
  • 11-Hexadecyn-1-Al
  • 9-Hexadecyn-1-Al
  • Z-11-Hexadecen-1-Al
  • Z-9-Hexadecen-1-Al
  • E-3-Octene-1-Ol
  • Z-3-Octene-1-Ol
  • E-3-Nonen-1-Ol
  • Z-3-Nonen-1-Ol
  • Z-6-nonen-1-Ol
  • Z-6-Nonen-1-Al
  • 3-Methyl-2-Cyclohexenone
  • 3-Methyl-2-Cyclohexenol
  • 3,3-Dimethyl-2-Cyclohexanone

Typical Process Capabilities:

  • Bromination, various ways
  • Chlorination using Thionyl Chloride, Phosphorus Pentachloride/trichloride, etc.
  • Dehydrohalogenation
  • Sodium/ Ammonia low temperature coupling
  • Sodamide or Lithium amide coupling
  • Grignard reaction
  • Metathesis (exploring presently with Noble Laurette chemist and European company)
  • Palladium based couplings like Sonagashira
  • Hydrogenation with state-of-the art catalysts. We are developing special catalysts for various application
  • Butyl Lithium (BuLi) chemistry
  • Low temperature chemistry (capable of doing liquid ammonia as solvent)
  • High level fractionation with magnetic equilibration
  • Biotransformation with special enzymes
  • Asymmetric catalysis for chiral chemistry
  • Boronic coupling like Suzuki or Negishi style
  • Catalytic Air Oxidation
  • Bleach Oxidation

ITEMS IN STOCK

  • 10-Undecyne-1-Ol
  • 15-Pentadecyne-1-Ol
  • 11-Hexadecyne-1-Ol
  • 9-Decyne-1-Ol
  • Ethyl-4-Pentynoate