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LEAF ALCOHOL

Cis-3-Hexenol; (z)-3-Hexen-1-ol

CAS No. 928-96-1

FEMA: 2563

cis-3-Hexen-1-ol, abbreviated as (Z)-3-hexen-1-ol is known as leaf alcohol. Leaf Alcohol is a very important aroma ingredient and is one of the most popular fragrance Ingredient in F&F industry. It has powerful green note resembling fresh Green Grass. In small amounts it gives top-notes of floral fragrance like Lilac. In Flavor formulation, it adds sweet green note to all fruit flavors like Paech Apple & Pear. It is a colorless oily liquid with an intense grassy-green odor of freshly cut green grass. Leaf alcohol also has been recognized as a semiochemical.

cis-3-Hexen-1-ol is an alcohol and its esters are also important flavor and fragrance ingredients.

Also, the leaf aldehyde, which is cis-3-Hexenal has stronger smell but is unstable.

It is traditionally manufactured from Sorbic alcohol by using Chromium catalyst for hydrogenation. Hexavalent Chromium is now classified as highly toxic, Carcinogenic and environmentally hazardous in nature, hence, this catalyst in now not preferred at all creating a shortage for leaf alcohol worldwide and scrambling for availability while the price has been spiralling upwards.

At ChemHub, we have developed two new processes eliminating use of hazardous Chromium catalyst. These new processes are environment friendly Green Chemistry.

 

Leaf Alcohol can be used to make other perfumery chemicals like

Leaf Acetate (cis-3-hexenyl acetate, CAS No: 3681-71-8)

Leaf Tiglate (cis-3-hexenyl tiglate, CAS No: 67883-79-8)

Leaf Aldehyde (cis-3-hexenyl aldehyde, CAS No: 6789-80-6)

 

We plan to offer all these ingredients, June onwards.

If you are interested, please contact us for further information:

ChemHub, Inc.

3, Crossman Road South,

Sayreville, NJ 08872

Phone: 908-548-0790

Email: [email protected]

url: www.chemhub.com

Chiral Chemistry at ChemHub

ChemHub is a CMO and CRO-dedicated company that focuses on small and commercial-scale production of pheromones, fine chemicals, fragrances, and flavors. Since its inception, ChemHub has constantly been redefining various chemistry solutions utilizing chiral chemistry for the fine chemical industries. By concentrating on the ethos of reinvention, redefinition, and rediscovery, ChemHub aims to provide path-breaking solutions to clients. The company offers four different services – custom synthesis, process development, analytical support, and chiral chemistry while employing them in production campaign for three main areas of Flavor & Fragrances, Pheromones and Specialty chemicals. ChemHub has excellent experience in customized chiral chemistry solutions and the production of complex and high-value chemicals in a critically differentiated manner using enabling process technologies.

ChemHub Chiral Chemistry

Although phenomenal research has been done at the academic level concerning chiral chemistry, its application has been challenging on a commercial scale. ChemHub has tried to break this loop by engaging our decades of scale-up experience with chiral chemistry in a revolutionary yet cost-effective manner knowing that chiral chemistry is an indispensable tool for producing optically active molecules. Likewise, chiral chemistry’s role in maximizing safety and efficacy is magnanimous and unavoidable as the usage of chiral molecules are reduced significantly as the other non-active chiral molecules will not be required. The sensitive nature of chiral resolutions and asymmetric chiral synthesis in conjunction with their significance in essential areas of drug development, makes it imperative to choose a responsible and trustworthy and competent company like ChemHub. The GOOD MANUFACTURING policies of the company are complemented with the values of integrity, reliability, and innovation means that Pharma and chemical sectors can depend on ChemHub for best solutions at a reasonable cost. ChemHub has accomplished multiple projects involving the process for the separation of racemic compounds into their enantiomers and diastereomers within the realm of stereochemistry. Simultaneously, the asymmetric chiral synthesis that ChemHub has developed using both organometallic catalysts and enzymes as biocatalysts fosters an efficient and effective route in API development and waste minimization.

ChemHub has implemented innovative process for the separation of racemic compounds into their enantiomers and diastereomers within the realm of stereochemistry. ChemHub’s chiral solutions open broader perspectives for the challenges confronting chemists to produce effective and simple solutions.

ChemHub possesses versatile and extensive experience with chiral catalysts and works with a significant number of enzymes. Some of the strongholds of ChemHub include

  • Asymmetric Organometallic catalyst to stereospecific enantiomer or diastereomer
  • Asymmetric material using enzymes – bio-catalysis
  • Resolution and separation of stereoisomers

Why Choose ChemHub’s Chiral Chemistry: A Crisp Overview

Premised on a robust foundation of competent technical experts, ChemHub develops and scales up a diverse range of chiral synthesis solutions for the benefit of its customers. The company strives to provide its clientele within the chemical industry to have an optimal and economic route characterized by purity and efficacy. ChemHub has the necessary training and mindset to develop high quality chiral synthesis to generate complex chiral molecules at a reasonable cost. As a result, the company is equipped to dispense an array of chiral scaffolds to their customers from various segments of chemical industries. ChemHub’s ingenious technical prowess coupled with immaculate process understanding and collective experience means that the needs of even the most complex chemistry requirements are adequately met.

ChemHub’s team has the capability and extensive knowledge of chiral chemistry and experience with chiral molecules. As a result, they are adept at helping customers choose optimal processes and achieve a product that caters to particular requirements suiting their budget. Through their multi-faceted chiral capabilities, ChemHub helps their esteemed clients achieve a product to their satisfaction. Thus, ChemHub helps customers to obtain the products with the desired qualities through a wide assortment of chiral competencies and abilities.

What Makes ChemHub’s Chiral Chemistry Special?

  • Cutting-edge Collaboration – ChemHub’s chiral chemistry solutions reach their culmination through intensive collaborations with academic and technical institutions to ensure that their client receives the best of both worlds – academic efficiency and commercial applicability.
  • Diversity – One of the biggest strengths of ChemHub is its versatility in terms of chiral chemistry services. In addition to asymmetric reduction, kinetic resolution, and stereoselective epoxidation, the company also deals in conventional separation of stereoisomers, green chemistry by use of biocatalysts, and so forth.
  • Holistic and simplistic Prowess – What makes ChemHub stand alone from others is its all and ever encompassing experience in complex chemistry, process design, and optimization. They add value to their chiral chemistry services by augmenting all-around benefits while on the endless learning curve to understand more.

Advantages of Opting for ChemHub

Some of the veritable advantages of opting for ChemHub as your chiral chemistry partner are

  • Listen to our clients and discuss
  • Strict quality control
  • Quality identification of synthetic products
  • Premium-quality chiral-related synthetic services
  • Top-notch and complex molecules
  • Years of experience in chiral chemistry to meet the specific needs of clients
  • Provision of comprehensive and well-thought-out services

Top Five Key Differentiators of ChemHub

  1. Genuine Scientific Collaboration – ChemHub prides itself on having a collaborative and straightforward way of working. They strive to transform the traditional perceptions of CMO and CRO-focused companies by adhering to the ethos of service, science, and passion.
  2. Excellent Operations – Being located in New Jersey, chemical hub of the US, ChemHub’s facilities are meticulously designed to adapt to the needs of chemist sectors. Equipped with state-of-the-art GLR and SS equipment, the chiral chemistry solutions of ChemHub operate under GMP and GMP-like conditions.
  3. Competent Team – The team of ChemHub is committed to putting their customers’ products first and delivering superior services and manufacturing solutions.
  4. Revolutionary Process Technologies- The continuous innovation and breakthroughs of ChemHub are what sets it a class apart from the rest. ChemHub relentlessly tries to expand its capabilities around a wide assortment of emerging and enabling technologies to maximize the value of services for its esteemed clientele by delivering critically differentiated products.
  5. Ethics of Care – The ethos of ChemHub is such that the entire team diligently tries to provide the highest standards of safety, sustainability, quality, and compliance to their customers.

Concluding Thoughts

Since its inception, ChemHub has successfully pioneered the domain of chiral chemistry. Moreover, it has also synthesized more than 10000 compounds, particularly in the pharmaceutical and biotech industries. The company also maintains vital strategic relationships with several research and manufacturing partners for raw material control, quality control, process control, and so forth. The many achievements of ChemHub in the domains of custom synthesis, process development, and high-quality product delivery make it a crucial and recognizable player in the CRO and CMO world. Thus, ChemHub has been at the forefront of revolutionizing chiral chemistry through innovative, groundbreaking, and novel trajectories. ChemHub promises its clients quality products, competitive pricing, superior service, and IP protection.

Analytical Support at ChemHub

ChemHub is a CMO and CRO-oriented company that engages in research and investigation of custom chemistry challenges and products for fine chemicals, pheromones, semiochemicals, flavors, and fragrances industries. Recently, the company also displayed an excellent capability to produce OLED materials and specialty material in the fine chemical industries. Both small-scale and commercial-scale industries are the target clientele of ChemHub. It is noteworthy to mention that ChemHub has extensive organic chemistry research experience with high-level trained staff to offer dedicated, quality and uncompromising services in analytical support, process development, and chiral chemistry.

Since its inception, ChemHub has been at the forefront of offering complete analytical support and method development coupled with comprehensive QS data packages, including structure elucidation and data interpretation. Through its state-of-the-art analytical tools such as NMR, GC, optimal rotation, KF titration, and so forth, ChemHub aims to dispense optimal support to its clientele in a timely fashion, at competitive prices, and within intellectual property protection. Some of the chemical analysis services that ChemHub offers, include –

  • Analytical Method Development
  • Data Interpretation
  • GC (Chiral and non-chiral columns)
  • GC-MS
  • HPLC (Chiral and non-chiral columns)
  • NMR (multi-nuclei and 2-D)
  • FT-IR
  • Optical rotation
  • Karl-Fischer Titration
  • UV-VIS
  • DSC
  • Stability testing

Thus, ChemHub is nearly one-stop destination for all analytical support related to the chemical and pharmaceutical industries. We have arrangements to provide other analytical services, such as,

  • Heavy metal
  • Toxicity
  • Microbiological assay

Importance of ChemHub’s Analytical Support

It would not be erroneous to say that analytical testing is the DNA of all pharmaceutical and chemical industries. Analytical support is essential for all kinds production campaign for quality control and process monitoring. ChemHub’s analytical support helps our own production and process control. ChemHub’s Analytical support helps businesses to manufacture, conduct research, and development, validate, and execute GCP, GLP, and cGMP analytical methods that range from routine to highly complex programs. First, the company identifies, determines, quantifies, and purifies a substance. After that, steps like separating the components of a solution or mixture or determining the chemical compounds are also taken into account.

With the inundation of FDA regulations and customer lawsuits, the significance of rigorous testing has escalated in pharmaceutical industries. It is in such a context of stringency that the analytical support mechanism of ChemHub comes into the picture. The impact of the increasingly regulated environment puts a lot of pressure on drug developers, and the GOOD MANUFACTURING practices of ChemHub act as the knight in shining armor by alleviating some of their rudimentary responsibilities. The four pivotal domains that set the analytical support of ChemHub a class apart from the rest are –

  • Regulatory compliance to CGMP-CGLP guidelines
  • Accessibility and professional competency that galvanizes the rigorous execution of a project
  • Quality Control
  • Quality Assurance
  • Affordability

ChemHub’s Technology Package and Analytical Support: The Perfect Duo

ChemHub aims to combine its excellent analytical support solutions with a holistic technology package to ensure that its clients get the best of both worlds.

  • The company ensures that its analytical support is robustly operable and has a practical approach.
  • Likewise, the cost-efficiency of the entire process is also prioritized. One of the main reasons ChemHub stands out among its clients in the pharmaceutical industry is its solemn concentration on competitive pricing.
  • The green energy goals through analytical support also form an integral part of the functionality of ChemHub.
  • The quality that ChemHub offers in its analytical support and testing procedures is unmatched.
  • Lastly, safety and IP transfer are two pillars that ChemHub diligently focuses on.

Top Five Reasons to Choose ChemHub for Analytical Support

ChemHub has a reputation for being the reliable and consistent at what they do! The ethos of ChemHub – responsiveness, reliability, innovation, and teamwork – implies that ChemHub will prioritize their clients’ needs and offer support that speaks to the unique endeavors of a project.

  1. Certification – ChemHub offers Kosher certified food-grade materials. We are also FDA food facility registered.
  2. In the area of innovation, ChemHub shines bright as it produces its products with the best GLR and SS equipment under the ambit of GMP-like conditions.
  1. Flexibility – ChemHub makes sure that its customers get flexibility and their requirements are being taken care of. It offers distinguishable merits in terms of price, quality, and deliverables like removal of unwanted impurity, better purity, and likewise are considered with utmost sincerity. Thus, choosing ChemHub means choosing a CRO and CMO-oriented company that listens, communicates, and pledges to offer the optimal solutions. ChemHub prides itself on long-term client engagement and relationships and acknowledges the significance of an optimally symbiotic relationship in an industry like the chemical and pharmaceutical sector.
  1. Long-term Client Relationship – Many of the customers of ChemHub have been long-term clients who always return owing to the excellent customer engagement offered by the organization. ChemHub pays a lot of attention to customer retention and satisfaction through viable communication and collaborative measures.
  1. Optimized Solutions – ChemHub ensures that they disseminate the most suitable and optimal analytical support solutions to their clients. The company ensures that its recommendations, plans, and layouts are customized to meet its customers’ diverse and disparate requirements. Moreover, ChemHub leaves no stone unturned to provide analytical support quality, cost-effectiveness, and reliability.
  1. Innovation – ChemHub strives to offer optimal and the most suitable analytical support solutions for every client. The company’s innovative and groundbreaking plans for analytical support are appreciated and sought-after by various sectors.

Concluding Thoughts

ChemHub aims to provide optimal, satisfactory, and the most suitable analytical support solutions to their clients by co-opting top-notch and highly complex analytical tools. The company’s prowess is in the dexterity that it displays while engaging with analytical support tools and processes like Karl-Fischer Titration, Optical Rotation, Data Interpretation, and so forth. ChemHub’s combination of qualified professionals with premium technology means that the needs of the drug developers are served to the best possible extent. Likewise, its salient focus on timely delivery, competitive pricing, and high quality provide it with an edge. Thus, without any doubt, doubt ChemHub strives to be reliable trustworthy partner in the crowded CMO and CRO market. Thus, ChemHub’s goal as a CRO and CMO-focused company to deliver best services possible in analytical support to their clients in the pharmaceutical and other chemistry sectors. ChemHub has a mission to become a comprehensive company within the domain of CMO and CRO.

Camphanediol | (+,-)-exo,exo-2,3-Camphanediol

Info: Camphanediol, High purity Camphanediol, Camphanediol in New Jersey, Exo-exo-Camphane diol, Exo,exo-2,3-Camphanediol, (+,-)-exo,exo-2,3-Camphanediol, CAS No: 56614-57-4, Camphanediol as Cosmetic Ingredient, Camphanediol Data

This is cosmetic/functional ingredient category. We are making ultrapure high quality material and is more specifically known as Exo-exo Camphanediol. Other manufacturers are doing more exo-endo derivative which is lower quality.

  • CAS Number: 56614-57-4
  • Molecular Formula: C10H18O2
  • Mol. Wt.: 170.25
  • Mp: 250-252 0C
  • Assay: >96% chemical purity; >97% isomeric purity
  • Synonyms: (1R,2S,3R,4S)-rel-1,7,7-Trimethylbicyclo[2.2.1]heptane-2,3-diol
  • Appearance: White crystalline solid

(+,-)-exo,exo-2,3-Camphanediol is utilized as a conditioning agent, affording a soft texture and feel to hair and skin. It is also known to increase microcirculation, leading to its use in several products in the cosmetics industry. Moreover, it has found application as a component in protective surface coatings.

The most common route to (+,-)-exo,exo-2,3-camphanediol (Isomeric purity: >94%) is via the reduction of camphorquinone with hydride reagents such as LiAlH4 and NaBH4.[i]­­­­,[ii] However, LiAlH4 is a toxic and pyrophoric reducing agent with poor solubility in common ether solvents and requires the use of strictly anhydrous reaction conditions. On the other hand, the milder NaBH4 provides the diol product in very low yields.[iii] The alternate synthesis via catalytic hydrogenation over Raney Ni necessitates the use of high pressures (~1000 psi of H2) and provides the (+,-)-exo,exo-2,3-camphanediol in poor diastereoselectivities.1

At Chemhub, we have developed a novel, mild reduction of camphorquinone to (+,-)-exo,exo-2,3-camphanediol in high yields and in excellent isomeric purity (>97%). The scalability and robustness of our method is particularly attractive, providing multi-kilogram quantities of (+,-)-exo,exo-2,3-camphanediol.

This is cosmetic/functional ingredient category. We are making ultrapure high quality material and is more specifically known as

Exo-exo Camphanediol. Other manufacturers are doing more exo-endo derivative which is lower quality.

Keywords: Camphanediol, High purity Camphanediol, Camphanediol in New Jersey, Exo-exo-Camphane diol, Exo,exo-2,3-Camphanediol, (+,-)-exo,exo-2,3-Camphanediol, CAS No: 56614-57-4, Camphanediol as Cosmetic Ingredient, Camphanediol Data

Tags: Camphanediol, High purity Camphanediol, Camphanediol in New Jersey, Exo-exo-Camphane diol, Exo,exo-2,3-Camphanediol, (+,-)-exo,exo-2,3-Camphanediol, CAS No: 56614-57-4, Camphanediol as Cosmetic Ingredient, Camphanediol Data

Pheromones, Semiochemicals and Intermediates

The terminology of pheromones came into existence in the 1950s when Peter Karlson and Martin Luscher began conducting research. Pheromones are organically occurring chemicals that trigger behavioral responses in another member of the same species. Nowadays, synthetic pheromones have become a crucial part of the pheromone industry to control insects and is alternative solution to pesticide industry.

Unlike pesticide, pheromones are required in minute amount and replace toxic pesticide which not only destroy the soil quality, but also pesticide residue can stay in the crops which can be toxic and carcinogenic. Pheromones (Semiochemicals) are an eco-sensitive way of dealing with pest infestation, controlling pest behavior, and managing forests.

ChemHub deals in a plethora of pheromones and semiochemicals, and, offer extraordinarily premium quality materials optimal for Pheromone application at a reasonable price.

Few examples of Pheromones supplied by ChemHub. Please visit chemhub.com for more information

  1. (-)-Verbenone, CAS number: 1196-01-6

In simple words, we can define Verbenone as a conventional pesticide that is non-toxic to pests and the environment. It is a registered product within the purview of EPA. It is an anti-aggregation pheromone for various kinds of bark beetles like the Southern Pine Beetle, Western Pine Beetle, and so forth. ChemHub supplies top-quality Verbenone in aluminum containers for use by chemists and druggists.

  1. 4-Methyl-5-nonanone, CAS number: 35900-26-6

ChemHub supplies one of the best quality 4-Methyl-5-nonanone in the US.

  1. (Z)-5-Decen-1-yl acetate, CAS number: 67446-07-5

If you are looking for the best quality (Z)-5-Decent-1-yl acetate Pheromones, then contact ChemHub. We have supplied the intermediates in the past.

  1. 3-Methyl-2-Cyclohexenone, CAS Number: 1193-18-6

It can be used as a pheromone and also is a precursor to Ball Weevil pheromone which is Grand Lure. Talk to us at ChemHub if you are looking for it. We can make and supply all four types of Grand Lure or the intermediates as precursors.

  1. 3,3-Dimethylcyclohexanone, CAS number is 2979-19-13

It is a pheromone intermediate precursor for Ball Weevil pheromone. This is also a precursor to Grand Lure and contact us for further information. We can make all components of Grandlure.

  1. z-7-Tetradecenal, CAS number: 65128-96-3

This pheromone is for Spaelotis clandestine. We have recently made it in a very innovative way and did scale up. Contact us for further information

  1. 11-Hexadecyne-1-ol, CAS number: 65686-49-9

This is an intermediate for quite a few pheromones. Please contact us for further information.

  1. 10-Undecyn-1-ol, CAS number: 2774-84-7

This is an important intermediate leading to quite a few pheromones. ChemHub deals in the top quality and can provide the final pheromones as well. Please contact ChemHub for further information.

  1. (e,z)-2,13-Octadecadien-1-al, CAS No: 99577-57-8

We have recently made it for one of our client for a good savings and is completely satisfied. Please contact ChemHub for more information.

What Is ChemHub all About?

ChemHub is a CRO and CMO oriented company based in New Jersey, US, that serves the pheromone and intermediates, along with fragrance, and flavor ingredients. The company’s focus is on small and medium-sized enterprises looking for reliable, trustworthy, and diligent services. The team of ChemHub has expertise to handle customized products and complex high-value chemicals with ease and dexterity. The company has a reputation for being the best at what they do! The ethos of ChemHub – responsiveness, reliability, innovation, and teamwork – implies that ChemHub will prioritize your needs, and they will take care of all the technical hassles. The chemical industry is in dire need of accountable companies that fit into excellent certification criteria and deliver immaculate quality. Moreover, ChemHub’s experienced and strategic team can work with you mean to offer rare and hard-to-find materials at an affordable price.

Why Choose ChemHub?

ChemHub stands out as a CRO and CMO focused company because of its well-developed and streamlined process coupled with its robust control and execution. The extensive manufacturing capacity of ChemHub, in conjunction with its affordable price and high quality, makes ChemHub stand alone from other vendors. In the area of innovation, ChemHub shines bright as it produces its products with the best GLR and SS equipment under the ambit of GMP-like conditions. Furthermore, the purification process of chemical compounds is as stringent as it can get, with processes like fractional distillation and crystallization being prioritized. Lastly, all production processes of ChemHub are free from halogenated solvents.

In addition to its fantastic production and supply ventures, ChemHub makes sure that its customers get flexibility and their requirements are being taken care of. It offers distinguishable merits in terms of price, quality, and deliverables like removal of unwanted impurity, better purity, and likewise are considered with utmost sincerity. Thus, choosing ChemHub means choosing a CRO and CMO oriented company that listens, communicates, and pledges to offer the optimal solutions. ChemHub prides itself on long-term client engagement and relationships and acknowledges the significance of an optimally symbiotic relationship in an industry like the chemical and pharmaceutical sector.

Services and Products Offered by ChemHub

ChemHub is a pioneer in delivering technology packages that serves the following objectives –

  • Green Environmental Resonance
  • Cost-effectiveness
  • Excellent Quality
  • Robust Operation
  • Safety
  • Technology Transfer

ChemHub has expertise in the following three areas –

  • It offers CRO and CMO support that is reliable and cost-effective to clients engaged in the pheromone and F&F industry.
  • The manufacturing and custom research services offered by ChemHub are exemplary and reliable.
  • ChemHub also manufactures and supply specialty chemicals and intermediates.

In addition to pheromones and semiochemicals, ChemHub also deals in flavor, fragrances, and fine chemicals. The company’s founder, Subir Chakraborty, devised ChemHub for creative and strategic technology plans that drive growth for chemical and pharmaceutical industries while offering cost-effectiveness and constant improvement. Since its inception, ChemHub has successfully synthesized more than 1000 compounds, primarily in the Biotech and Pharma industries. The company has been serving customers by dealing with diverse chemical reactions, innovating the available chemistry, and designing pieces of equipment that add value. It has collaborated with several global companies and maintains strategic relationships with various research and manufacturing partners for Raw Material Control, Quality Control, and Process Control.

Concluding Thoughts

ChemHub is a pioneer CRO and CMO based company that provides the best quality pheromones and semiochemicals in the safest possible ways. The company has been at the forefront of revolutionizing pheromone and semiochemical production process through its state-of-the-art production, purification, and distribution mechanism.

Process Development at ChemHub

ChemHub has the necessary quintessential experience of process development for specialty materials and scale up faster to help clients to enter the market place. Its primary clients include small and commercial scale production houses in the pheromone, flavors, fragrance, and fine chemical industries. Since its inception, ChemHub has been providing dependable and diligent chemistry to its esteemed clientele in various sectors. Likewise, the company prides itself on providing custom research and manufacturing services coupled with innovative solutions to chemistry challenges for various applications, formulations and any special requirements. So, without further ado, let us glance at the process development at ChemHub, and its various entailments.

Process Development at ChemHub: A Brief Overview

ChemHub’s process development is a multifaceted mechanism that is premised on customization and personalization. Its primary ethos include:

  • Fact-based
  • Innovation
  • Economics
  • Quality
  • Reproducibility
  • Sustainability
  • Executable
  • Sustainability
  • Compatibility
  • Customer satisfaction

ChemHub’s process development entails a diverse matrix of solutions for their clients. The top five areas of process development that ChemHub pioneers in include:

  1. Route Scouting – It is that part of process development wherein the most feasible or viable route or synthetic scheme is designed to synthesize chemicals premised on safety, environmental, legal, economic, and control and throughout GOOD MANUFACTURING principles. ChemHub ensures that the route scouting mechanism is ideally tailored to fit the needs of their particular clients so that there are no problems concerning scaling, technology transfer, stability, purity, and likewise. Moreover, the various streamlining steps that ChemHub adopts result in cost-efficiency, reduced wastage, premium quality, and time savings for their clients in the Pharma and fine chemical industry.
  2. Economic Feasibility – ChemHub has a unique and foolproof method of conducting feasibility studies wherein the project’s assessment and practicality get prime importance. The company is equipped to diligently uncover the strengths, weaknesses, and gaps in their clients’ ventures and conjure an ideal trajectory to deal with the same.
  3. Green Chemistry – It is the design of chemical products and processes to reduce and mitigate the generation of hazardous by-products. The Green chemistry solutions that ChemHub offers are structured on being multi-disciplinary, pollution prevention at the molecular level, scientific innovations to tangible environmental problems, and constructing chemical products and processes that facilitate the reduction of intrinsic hazards. Furthermore, ChemHub’s green chemistry tools and instruments are applicable across the lifecycle of a chemical product, including design, manufacture, use, and disposal.
  4. In-process Monitoring Control – It is the instrumentation that monitors and controls a chemical process. ChemHub has been delivering top-notch in-process monitoring control to their clients so that optimal levels of production consistency, economic efficiency, and safety control can be achieved.
  5. Quality Improvement – ChemHub’s quality improvement and assurance mechanism have helped various significant Pharma and fine chemical industry players make significant performance improvements. They focus on dispensing sustainable results through trajectories that are flexible and scalable. The quality improvement rhetoric of ChemHub is based on innovation, creativity, and practicality.

In addition to the areas mentioned above, ChemHub also specializes in other domains of the process development spectrum such as –

  • Economic feasibility versus robustness
  • Hazard reduction
  • Increase in overall safety
  • Process optimization versus process maximization: upstream and downstream
  • Data analysis and actionable intelligence to identify areas of improvement
  • Assistance in the selection of the optimal equipment at a reasonable cost
  • Reproduction and versatile outcomes

What Makes ChemHub Stand Alone?

With the plethora of CRO and CMO oriented companies that have inundated the marketplace in recent times, what makes ChemHub is their immaculate accountability. The company’s four pillars – responsiveness, reliability, innovation, and teamwork – mean that they prioritize their clients’ needs and try to resolve all the issues through state-of-the-art chemistry solutions. The mammoth-sized manufacturing competency of ChemHub coupled with flexibility, affordability, and premium quality sets the company a class apart from the rest.

It is noteworthy to mention that the production efficiency of ChemHub shines bright as they are manufactured and executed with the best GLR and SS equipment under the umbrella of GMP-like conditions. Likewise, the purification process of chemical compounds is as stringent as possible, with processes like fractional distillation and crystallization being prioritized. Ultimately, all production processes of ChemHub are free from halogenated solvents.

ChemHub’s Orientation to Their Customers

ChemHub ensures that they disseminate and decipher the most suitable and optimal solutions for their clients. In a world characterized by ‘information overload,’ the adept team of ChemHub strives hard to ensure that all their recommendations, plans, and layouts are customized to meet their customers’ diverse and disparate requirements. Likewise, the company makes sure that there is no compromise in quality, cost-effectiveness, and reliability. The varied clients of ChemHub appreciate the company’s effort to boost profitability and margins.

Many of the customers of ChemHub have been long-term clients who always return owing to the excellent customer engagement offered by the organization. ChemHub pays a lot of attention to customer retention and satisfaction through viable communication and collaborative measures. Lastly, ChemHub makes sure that its customers get flexibility and their requirements are being taken care of. It offers distinguishable merits in terms of price, quality, and deliverables like removal of unwanted impurity, better purity, and likewise is considered with utmost sincerity.

Concluding Thoughts

ChemHub is a pioneer CRO and CMO based company that provides the best quality pheromones and semiochemicals in the safest possible ways. The company has been at the forefront of revolutionizing process development through innovative, groundbreaking, and novel trajectories. ChemHub promises all its clients quality products, competitive pricing, superior service, and IP protection. Since its inception, ChemHub has successfully synthesized more than 10000 compounds, primarily in the Biotech and Pharma industries. The company has been serving customers by dealing with diverse chemical reactions, innovating the available chemistry, and designing pieces of equipment that add value. It has collaborated with several global companies and maintains strategic relationships with various research and manufacturing partners for Raw Material Control, Quality Control, and Process Control.

Thus, Please make ChemHub your one-stop destination for process development and further needs. Look no further and contact the competent team of ChemHub for personalized solutions to your projects, queries and concerns.

Custom Synthesis at ChemHub

ChemHub is a CRO and CMO focused company that serves the pheromone, flavor, fragrances, and fine chemical industries. The company strives to provide uncompromising and high-value chemical solutions at cost-effective rates. ChemHub’s primary ethos of reliability, dedication, and excellence means that its clientele is prioritized and offered the best of what is available. As a result, the company has been relaying customized campaigns to produce complex and valuable chemicals at a reasonable price and in a much more pleasant and productive way.

ChemHub and Fine/Specialty Chemicals: Everything You Need to Know

ChemHub is the quintessential nucleus of fine or special chemical deliverables. ChemHub specializes in gram to kilogram synthesis and manufacturing fine or specialty chemicals and active pharmaceutical ingredients to metric ton levels. A few examples of fine chemicals that the company deals with include

  • 4-Methyl-5-nonanol – ChemHub offers premium quality 4-Methyl-5-nonanol (CAS 15410-44-2) in a well-packaged container. It is a pheromone of the sugarcane weevil M. hemipterus. Its molecular formula is C10H220, and its formula weight is 158.28.
  • 2-(3′-chloro-[1, 1′-biphenyl]-3-yl)-4, 6-diphenyl-1, 3, 5-triazine – Its CAS number is 1443049-83-9. Its molecular formula is C27H18ClN3.
  • 9-bromonaphtho [2, 1-b] benzofuran – It is a fine chemical that ChemHub deals in. Its CAS number is 1256544-27-0. The molecular formula of 9-bromonaphtho [2, 1-b] benzofuran (CAS 1256544-27-0) is C10H9BrO.
  • Boronic acid (four-bromonaphthalen-one-yl) – Its CAS number is 145965-14-16, and its ChemHub product code is CH-OLED-0045. The chemical formula of the compound is C10H8BBrO2. Some of the other properties of (4-bromonaphthalen-1-yl) boronic acid (CAS 145965-14-16) include a molecular weight of 250.88
  • [1, 1′-biphenyl]-3-ylboronic acid – Its CAS number is 5122- 95-2. The molecular formula of the compound is C12H11BO2. Some of the other chemical properties of [1, 1′-biphenyl]-3-ylboronic acid (CAS 5122- 95-2) include a molecular weight of 198.025.

In addition to the aforementioned fine chemicals, ChemHub is engaged in the custom synthesis of a plethora of other special chemicals like (2-methaoxynapthalen-1-yl) boronic acid (CAS 2401-47-6), 1-Bromo-2-methoxynaphthalene (CAS 3401-47-6), (4-(10-(naphthalene-2-yl) anthracen-9-yl) phenyl) boronic acid (CAS 911390-81-3), and much more.

ChemHub’s Custom Synthesis: A Crisp Overview

In simple words, we can understand custom synthesis as the exclusive synthesis of the creation of compounds. ChemHub offers custom synthesis as per the requests of their clients, and all requirements regarding purity, scale, and methods are taken into account. It is noteworthy to mention that ChemHub is a CRO and CMO-oriented organization that enables the outsourcing of various research activities related to chemicals and produces tons of fine chemicals on multi-purpose plants. Some of the pioneering domains of ChemHub include –

  • Custom synthesis of compounds requiring complex multistep chemistry
  • Chiral asymmetric synthesis and solution of enantiomers and diastereomers
  • Synthetic Route development
  • Semi-synthetic route development from plan material
  • Extraction of natural products

Since its inception, ChemHub has been at the forefront of synthesizing a diverse range of chemicals. They have provided quality chemical products and services to support research and development feats in the pharmaceutical, biotechnology, chemical, pheromone, flavor, and fragrance industries. Their synthesis competencies range from milligram to kilogram scale and commercially producing advanced organic compounds. The team of ChemHub deals with the most refined chemicals so that their clients receive the best chemistry solutions.

Top Five Aspects That Make ChemHub Stand Alone

ChemHub delivers efficient and high-quality chemicals and chemistry solutions to its esteemed clients. All the manufacturing and production in ChemHub is executed with the best GLR and SS equipment under the ambit of GMP-like conditions. The company’s four pillars – responsiveness, reliability, innovation, and teamwork – mean that they prioritize their clients’ needs and try to shove away all their worries and wry through state-of-the-art chemistry solutions.

The key areas that make ChemHub notable include –

  1. Reliability – ChemHub is a CRO or CMO-oriented company that collaborates with its clients in the fragrance, pheromones, and pharmaceutical industries to deliver dependable and cost-effective chemistry solutions.
  1. Customization – One of the biggest strengths of ChemHub is its custom research and manufacturing competencies that serve the core needs of a few of the top Pharma and fine chemical industries of the world. Likewise, the company has been attending to the needs of its diverse clientele by boosting profitability through optimal custom or toll manufacturing.
  1. Innovation – ChemHub pledges to offer optimal and the most suitable solutions for every client. ChemHub’s innovative and groundbreaking plans for new chemicals are appreciated and sought-after by various sectors. Likewise, they act as ideal suppliers of specialized intermediates for pharmaceutical and specialty applications.
  1. Problem Solving – ChemHub’s practical yet unique and efficacious solution for novel chemistry challenges sets them apart from their peers. The company’s undaunted approach in dealing with unbeknownst challenges within the CRO and CMO circle provides them with a unique edge.
  1. Customer Engagement – ChemHub goes the extra mile to ensure that its customers are satisfied. They maintain superior quality customer service and communication with all their clients to get a firmer grasp on the needs and mandates of their clients. Thus, customer engagement, retention, and customer satisfaction are three crucial areas that ChemHub prides itself on.

Concluding Thoughts

Since its inception, ChemHub has successfully synthesized more than 10000 compounds, particularly in the pharmaceutical and biotech industries. The company also maintains vital strategic relationships with several research and manufacturing partners for raw material control, quality control, process control, and so forth. The many achievements of ChemHub in the domains of custom synthesis, process development, and high-quality product delivery make it a crucial and recognizable player in the CRO and CMO world.

Please contact ChemHub for more information and how we can make these pheromones for you.

Email: [email protected] Website: www.chemhub.com Phone: 908-548-0790

ChemHub is Reliable outsourcing partner for Flavor & Fragrance in New Jersey, US

We at ChemHub have a team of chemists dedicated with passion to offer our clients the best quality products at a reasonable cost. ChemHub offers a number of products including custom services to our valued customers. We value innovation, creativity, capabilities, and experience here at ChemHub. In this blog, we discuss the flavor and fragrance offered by ChemHub.

Flavor & Fragrance offered by ChemHub 

Flavors and fragrances are used in various applications ranging from cosmetics to food. At ChemHub, we offer a number of flavor and fragrance ingredients. Listed below are some examples of the flavors and fragrance ingredients offered by us. We plan to introduce a number of additional F&F ingredients in the near future.

  • Maple Furanone –Ethyl Fenugreek Lactone, widely known as Maple Furanone, is a strong and powerful tasting chemical. The flavor and aroma is nature identical to maple syrup and caramel. It works in the kitchen when coupled with sweet brown flavors like chocolate, caramel, maple, coffee, vanilla, and butterscotch. It’s also utilized in conjunction with smoky taste, most frequently in the form of meats. This chemical is extremely long-lasting when utilized in scent and requires pairing with equally tenacious and strong odored compounds to reach its full potential. This item is our signature item and the price is quite reasonable.
  • Caramel Furanone –Sotolon is a lactone with a distinctive smell, smelling like fenugreek or curry at large concentrations of caramel, maple syrup, or burnt sugar at lesser concentrations. Sotolon’s texture also contributes to the elusive flavor component, which we know as mouthfeel. It has a heavy “taste,” if that makes perfect sense. ChemHub makes this item in high quality and offer to clients at reasonable cost.
  • Delta-Nonalactone –Delta-Nonalactone is a clear liquid with really no color. It’s also recognized for its perfumery, culinary flavoring, Aromatic cosmetic soap detergent, and the fragrance industry. It’s a type of molecule discovered in bourbon whiskey. Delta-Nonalactone contains unique spicy and fruity undertones in addition to the traditional coconut taste, making it ideal for dairy, coconut, and meat applications. We have developed unique method to make it and supply worldwide.
  • Methyl Heptine Carbonate –Methyl heptine carbonate, abbreviated as MHC in short and is utilized in the flavor and fragrance business. It smells like vegetables and is employed in many other types of aromas. The MHC flavor has a pleasant melon aroma to it. This component is also used as a chemical synthesis intermediate. Methyl heptine carbonate is used to give scents and meals a “green” taste or flavor, similar to what you’d find in vegetables, plants, and cucumbers. ChemHub produces this chemical for a long time using a variety of techniques from the scratch. They are increasingly using renewable materials that aid in the preservation of the earth’s natural resources.
  • Methyl Octine Carbonate –Methyl Octine Carbonate is a greenish and floral fragrant compound that is frequently used in perfumery and flavoring. Like violet and cucumber, it has a fruity-vegetable top note with faint green undertones. Also, this molecule is used in the production of flower perfumes and outdoor goods, as well as tea.

All the products offered by ChemHub are Kosher certified. The flavors and fragrances listed here are just a sneak peek of what ChemHub can offer. There are more products to choose from, which we will add on our official website.

Why choose ChemHub? 

ChemHub is a dedicated contract research organization (CRO) and contract manufacturing organization (CMO) focusing on modest and commercial-scale production for customers in flavors and fragrance, pheromone, and fine chemical industries.

ChemHub has a lot of experience with tailored programs for high-value chemicals. Our expertise and smart JV collaborations enable us to produce difficult-to-find chemicals at a lower cost and productively. We encourage Integrity, Responsiveness, Reliability, Innovation, and Teamwork at ChemHub.

  • ChemHub offers a number of products to its clients, such as pheromones, flavors and fragrances, and other fine/specialty chemicals for diversified applications.
  • The expert professionals at ChemHub have decades of experience.
  • We explore capabilities and opportunities according to the demands of the client.
  • Our team will discuss your project with you and consider your valuable feedback.
  • ChemHub typically requires three to four months for the custom/campaign production of intermediates and semiochemicals.

ChemHub Key Features

  • The Production Process is Under Strict Control
  • Processes that have been well-developed and fine-tuned
  • Orders can be filled straight away if you need them.
  • Products are made at a reasonable cost, on a huge scale, and with good quality.
  • Key raw materials are under tight supervision and monitored

Core Strengths of ChemHub 

  • The design and synthesis of products using diverse chemistry is a key strength.
  • Handle all types of chemical reactions successfully to produce chemicals for our customers.
  • Offer differentiated price, quality, and other deliverables.
  • The elimination of undesired impurities and remove contaminant profile to suit F&F requirement and specification.
  • Greater yield leading to improved pricing, passing on cost savings to the customer.
  • Our ultimate purpose is to create value for our customers by inventing with the existing chemistry and design.

Production on a Large Scale and Certification 

  • Capacity is several tons each month, with the ability to expand as needed.
  • Each and every MT will have a COA.
  • Ability to provide a Certificate of Analysis (COA), a Food Allergen Certificate, and a GMO Certificate, and also maintain quality control.
  • The use of Kosher-certified and food-grade materials to produce materials.

ChemHub has excellent innovative techniques. 

  • Production is performed using the finest GLR and SS technology in a GMP-like environment.
  • Fractional distillation and crystallization are used in a strict filtration process.
  • There is no halogenated solvent in the operations.
  • Offer ultra-pure substances that are ideal for F&F, pheromone, and pharmaceutical purposes.

Customers’ Mission at ChemHub 

  • Provide the best suitable solutions to each client.
  • Provide a cost-effective, high-quality, and trustworthy delivery service.
  • Custom/Toll To improve the profitability of our clients, we manufacture exquisite chemicals.
  • Maintain outstanding customer service and communication with customers in order to grasp their needs better.
  • Establish a long-term relationship and commitment with customers.

Summary

For Process Control, Raw Material Control, and Quality Control, ChemHub maintains crucial strategic protocols and select appropriate manufacturing partners to produce exclusively for ChemHub only. ChemHub has manufactured over hundreds of chemicals, mostly for the F&F, Pheromone, pharma and biotech industries. Our goal is to produce and offer best quality products to our clients.

If you have any further queries, feel free to reach out to us at our contact number +1-908-548-0790. You can also mail us your queries [email protected]

Grandlure I, II, III, IV

Ball Weevil Beetle or Anthonomus grandis is a pest from Coleoptera Curculionidea family of insects. This beetle thrives on cash crop of Cotton.

(Image of Ball Weevil Insect on Catton ball and white colored Larva inside damaged cotton ball) 

Ball weevil is a serious pest for cotton in South America and Mexico since decades. Ball weevil infested cotton crop to 90% level. It travelled to United Sates from Mexico substantially damaging 87% crop in many states causing huge losses to the tune of Billion dollars. Sometimes they infest in homes and feed on cotton clothes.
 

First insecticide DDT enabled U.S. farmers again to grow cotton as an economic crop. DDT was initially extremely effective, but U.S. weevil populations developed resistance Methyl parathion, malathion, and pyrethroids were subsequently used, but environmental and resistance concerns arose as they had with DDT, and control strategies changed. Now a days it is controlled environment friendly Insect pheromones .
 

For control of Ball Weevil, we offer a group of pheromones (Male Aggression Pheromones) called Grandlures of high purity. Grandlure I & II are used mainly and Grandlure III & IV are used in less quantities.
 

Grandlure I : 1R,2S-cis-1-Methyl-2-Isopropenylcyclobutaneethanol (CAS No: 26532-22-9)

Grandlure II: (Z)-2-(3,3-Dimethyl)-Cyclohexyllideneethanol (CAS No: 26532-23-0)

Grandlure III: (Z)-(3,3-Dimethyl)-Cyclohexylideneacetaldehyde (CAS No: 26532-24-1)

Grandlure IV: (E)-(3,3-Dimethylcyclohexylidene)acetaldehyde (CAS No: 26352-25-2)


Reaction Scheme:

3-Me-2-Cyclohexenol

 

Please contact ChemHub for more information and how we can make these pheromones for you.

Email: [email protected]
Website: www.chemhub.com

Phone: 908-548-0790

Pheromones with 18 Carbon chain

10-Undecynol is starting material for 10-Pentadecynol and from 10-Pentadecynol we have developed technology to make following different molecules having chain of eighteen carbons:

  1. (e,z)-2,13-Octadecadien-1-ol [123551-47-3]
  2. (e,z)-2,13-Octadecadien-1-yl acetate [86252-65-5]
  3. (e,z)-2,13-Octadecadien-1-al [99577-57-8]
  4. (e,z)-3,13-Octadecadien-1-ol [66410-28-4]
  5. (e,z)-3,13-Octadecadien-1-yl acetate [53120-26-6]
  6. (z,z)-3,13-Octadecadien-1-ol [66410-24-0}

Above mentioned C-18 compounds in various combinations can be used as active pheromones ingredients for control different types of insects infesting variety of plants.

Compound-1 [(e,z)-2,13-Octadecadien-1-ol ] and Compound-6 [ (z,z)-3,13-Octadecadien-1-ol] in combination are useful to control pest Western Popular Clearwing ( Paranthrene Robiniea) found on Mulberry.

Compound -2 [(e,z)-2,13-Octadecadien-1-yl acetate] and Compound-5 [(e,z)-3,13-Octadecadien-1-yl acetate] are used in pest control of Leopard Moth ( Zeuzera Pyranea) which affects most of the orchards like Apple, Plum, Pear & Peach.

Compound-1 [(e,z)-2,13-Octadecadien-1-ol ] alone is used in other pest on Orchards that is Dog wood borer (Synanthedon scitula)

Compound 3 [(e,z)-2,13-Octadecadien-1-al] is pheromone for insect called as Webbing Clothe Moth ( Tineola Bisselliella) which is found in textile mills and textile warehouses.

Please contact ChemHub for more information and how we can make these pheromones for you.

Email: [email protected]
Website: www.chemhub.com

Phone: 908-548-0790